Glutamic acid or Glutamate is the most abundant excitatory neurotransmitter in the central nervous system of mammalians and a key molecule in metabolism.
The antagonists of this exciatatory neurotransmitter are the inhibitory transmitters with Serotonin and GABA being the most dominant. GABA is directly linked to Glutamate via the so-called Glutamine cycle thus allowing for a fast and subtle adjustment during the different physiological conditions.
Glutamate is involved in cognitive functions like learning and memory in the brain and has also been implicated in epileptic seizures.
The Glutamate ELISA (BA E-2400) is a sensitive assay for the quantitative determination of Glutamate in urine and is intended for in-vitro diagnosis. As part of the sample preparation, a simple and versatile extraction enables this assay to be highly specific, showing no cross-reactivity to Glutamine.
For research applications in various biological samples please contact us.